The game takes place in the DC universe and tells a story involving The Batman Who Laughs and his Dark Knights. These are "twisted" versions of members of the Justice League who debuted in the DC Comics series Dark Nights: Metal. As they fight to stop The Batman Who Laughs and his army from destroying everything they know, players take on the role of an agent from the 31st century tasked with leading the world's greatest super heroes against the overwhelming threat from the Dark Multiverse.