Granny relaxes in the yard with her feline friends when, out of the depths of the basement, her nemesis Dr. Meow appears with an evil new scheme: He created a powerful shrink ray to turn Granny into a pint-sized person. Faster than she can say meow mix, he zaps her with it, and now the diminutive Granny finds herself in a whole new predicament. Help Granny journey through the dangerous wilderness of her own backyard and find a way back to normal size.